- Product Details
Keywords
- Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2
- 140430-53-1
- Mca-PLGL-Dpa-AR-NH2
Quick Details
- ProName: Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-N...
- CasNo: 140430-53-1
- Molecular Formula: C??H??N??O??
- Application: Cancer Research
- ProductionCapacity: Metric Ton/Day
- Purity: 95%
- Storage: -20 ± 5 °C
- LimitNum: 0 Metric Ton
Superiority
Nanjing TGpeptide Biotechnology Co.,Ltd.("TGpeptide" hereafter), who is founded in 2019, located at Jiangbei New Material Industrial Park, is a professional enterprise enageged in researching, developing, manufacturing and sales of peptide, antibody and protein products and their technologies.
Range of Services:
1, Linear peptides: Quantity from mg to kg, up to 180 residues.
2, The range of purity: Crude、Desalted、>70%、>80%、>90%、>95%、>98%、>99%.
3, Peptide modifications: C-terminal modifications, N-terminal modifications, Fluorescence and Dye Labeling Peptides, Cyclic Peptides Synthesis, Phosphopeptides etc.
4, Peptides with different structures: Linear peptides, MAPs, Cyclic peptides etc.
5, Antigen peptides: KLH, BSA, 0VA coupling.
6, Different packages: we can make aliquots according to the demand of customers, and it's free.
Details
173P21 |
Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH? trifluoroacetate salt |
Mca-PLGL-Dpa-AR-NH? |
7-Methoxycoumarin-4-Acetyl-Pro-Leu-Gly-Leu-Dnp-(2,3-Diaminopropionyl)-Ala-Arg, amide |
C??H??N??O?? |
1093.16 |
140430-53-1 |
Synthetic |
-20 ± 5 °C |
Cancer Research |
Mca-PLGL-Dpa-AR-amide is a very sensitive FRET substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. Cleavage at the Gly-Leu bond separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher, resulting in an increase in fluorescence intensity. The kcat/Km values for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7·10? and 6.3·10? M?¹s?¹, respectively. |