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Home > Products >  Amyloid β-Protein (1-42)

Amyloid β-Protein (1-42) CAS NO.107761-42-2

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  • Product Details

Keywords

  • 107761-42-2
  • Amyloid
  • Aβ42

Quick Details

  • ProName: Amyloid β-Protein (1-42)
  • CasNo: 107761-42-2
  • Molecular Formula: C???H???N??O??S
  • Application: Alzheimer's Disease Antimicrobial & A...
  • ProductionCapacity: Metric Ton/Day
  • Purity: 95%
  • Storage: -20 ± 5 °C
  • LimitNum: 0 Metric Ton

Superiority

Nanjing TGpeptide Biotechnology Co.,Ltd.("TGpeptide" hereafter), who is founded in 2019, located at Jiangbei New Material Industrial Park, is a professional enterprise enageged in researching, developing, manufacturing and sales of peptide, antibody and protein products and their technologies.
   Range of Services:
1, Linear peptides: Quantity from mg to kg, up to 180 residues.
2, The range of purity: Crude、Desalted、>70%、>80%、>90%、>95%、>98%、>99%.
3, Peptide modifications: C-terminal modifications, N-terminal modifications, Fluorescence and Dye Labeling Peptides, Cyclic Peptides Synthesis, Phosphopeptides etc.
4, Peptides with different structures: Linear peptides, MAPs, Cyclic peptides etc.
5, Antigen peptides: KLH, BSA, 0VA coupling.
6, Different packages: we can make aliquots according to the demand of customers, and it's free.

Details

107P64
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 
Aβ42, β-Amyloid (1-42) 
C???H???N??O??S
4514.1
107761-42-2
Synthetic
-20 ± 5 °C
Alzheimer's Disease
Antimicrobial & Antiviral Peptides
Aβ 1-42, 42-residue fragment of amyloid precursor protein, has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. Aβ 1-42 readily forms neurotoxic oligomers at physiological pH. On the other hand, the peptide shows antimicrobial activity. The sequence of H-1368 corresponds to the human, bovine, canine, feline, ovine, guinea pig, and rabbit Aβ42 peptide.
The peptide has been used to detect amyloid β-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients through fluorescence correlation spectroscopy.
For detailed descriptions of the preparation of Aβ 1-42 monomers and protofibrils please see the papers of Jan, Hartley, and Lashuel, Stine et al. (2011), and of Broersen and colleagues. The findings of Ryan et al. indicate that 10% ammonia disaggregates Aβ42 more efficiently than HFIP. 

 

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